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文章更新 #45

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GuangchuangYu opened this issue Jan 4, 2024 · 0 comments
Open

文章更新 #45

GuangchuangYu opened this issue Jan 4, 2024 · 0 comments

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@GuangchuangYu
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GuangchuangYu commented Jan 4, 2024

  1. 现在支持非常多的物种,因为不是内置支持,而是先外部处理OrgDb,准备好GO注释。

即便是用户自己注释的新基因组,也能够分析,少去了搞OrgDb的门槛。

  1. 基于信息含量的几种方法是我用C++重写的,后来又有@alyst优化,现在的速度更快。

  2. 实现了新方法TCSS

  3. 支撑其它包的语义相似性度量,包括disease ontology, human phenotype ontology, mouse phenotype ontology, Medical Subject Headings等。

  • 可以结合一个GAF文件和TCSS方法,应用于蛋白上,可能更准确些 (或者可以做为example,用于写protocol之类的,不在新manuscript里)。
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