diff --git a/setup.py b/setup.py
index 864c25461..03077624f 100755
--- a/setup.py
+++ b/setup.py
@@ -546,9 +546,7 @@ def main():
             "test": TEST_DEPS,
         }
         kwargs.update(
-            python_requires=(
-                "!=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*"
-            ),
+            python_requires=">=3.6",
             extras_require=extras_require,
             zip_safe=False,
         )