diff --git a/.github/workflows/build-nuget-packages.yml b/.github/workflows/build-nuget-packages.yml
index 2fedbb7db1..70813c8bc0 100644
--- a/.github/workflows/build-nuget-packages.yml
+++ b/.github/workflows/build-nuget-packages.yml
@@ -75,8 +75,8 @@ jobs:
       - name: Download Mac-OS Artifacts from build job
         uses: actions/download-artifact@fa0a91b85d4f404e444e00e005971372dc801d16 # tag: v4.1.8
         with:
-          name: bin-macos-12
-          path: bin/ci-artifacts/bin-macos-12
+          name: bin-macos-13
+          path: bin/ci-artifacts/bin-macos-13
 
       - name: Build NuGet packages
         run: ./build.cmd BuildNuGetPackages
diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 6f62f84cfb..66ac919c15 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -17,7 +17,7 @@ jobs:
             log-dir: "/c/ProgramData/OpenTelemetry .NET AutoInstrumentation/logs"
           - machine: ubuntu-20.04
             log-dir: "/var/log/opentelemetry/dotnet"
-          - machine: macos-12
+          - machine: macos-13
             log-dir: "/var/log/opentelemetry/dotnet"
           - machine: otel-linux-arm64
             log-dir: "/var/log/opentelemetry/dotnet"
diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 53b8d72934..0d8a43123a 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -32,10 +32,10 @@ jobs:
       fail-fast: false
       matrix:
         test-tfm: [ net8.0, net7.0, net6.0, net462 ]
-        machine: [ windows-2022, ubuntu-20.04, macos-12, otel-linux-arm64 ]
+        machine: [ windows-2022, ubuntu-20.04, macos-13, otel-linux-arm64 ]
         exclude:
           - test-tfm: net462
-            machine: macos-12
+            machine: macos-13
           - test-tfm: net462
             machine: ubuntu-20.04
           - test-tfm: net462
@@ -45,7 +45,7 @@ jobs:
             containers: none
           - machine: ubuntu-20.04
             containers: linux
-          - machine: macos-12
+          - machine: macos-13
             containers: none
           - machine: otel-linux-arm64
             containers: linux
@@ -260,7 +260,7 @@ jobs:
       matrix:
         include:
           - machine: ubuntu-20.04
-          - machine: macos-12
+          - machine: macos-13
           - machine: windows-2022
           - machine: otel-linux-arm64
     runs-on: ${{ matrix.machine }}
diff --git a/.github/workflows/format-native.yml b/.github/workflows/format-native.yml
index 8eb605dd0a..80f7e32f23 100644
--- a/.github/workflows/format-native.yml
+++ b/.github/workflows/format-native.yml
@@ -12,7 +12,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        machine: [ windows-2022, ubuntu-20.04, macos-12 ]
+        machine: [ windows-2022, ubuntu-20.04, macos-13 ]
     runs-on: ${{ matrix.machine }}
     steps:
 
diff --git a/.github/workflows/release-publish.yml b/.github/workflows/release-publish.yml
index 13873c2f0f..e63ad34d7b 100644
--- a/.github/workflows/release-publish.yml
+++ b/.github/workflows/release-publish.yml
@@ -52,7 +52,7 @@ jobs:
             log-dir: "/c/ProgramData/OpenTelemetry .NET AutoInstrumentation/logs"
           - machine: ubuntu-20.04
             log-dir: "/var/log/opentelemetry/dotnet"
-          - machine: macos-12
+          - machine: macos-13
             log-dir: "/var/log/opentelemetry/dotnet"
           - machine: otel-linux-arm64
             log-dir: "/var/log/opentelemetry/dotnet"
diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index f5c030fd46..67608068cb 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -49,7 +49,7 @@ jobs:
       - run: cd bin-ubuntu-20.04 ; zip -qq -r ../opentelemetry-dotnet-instrumentation-linux-glibc-x64.zip . * ; cd ..
       - run: cd bin-otel-linux-arm64 ; zip -qq -r ../opentelemetry-dotnet-instrumentation-linux-glibc-arm64.zip . * ; cd ..
       - run: cd bin-windows-2022 ; zip -qq -r ../opentelemetry-dotnet-instrumentation-windows.zip . * ; cd ..
-      - run: cd bin-macos-12 ; zip -qq -r ../opentelemetry-dotnet-instrumentation-macos.zip . * ; cd ..
+      - run: cd bin-macos-13 ; zip -qq -r ../opentelemetry-dotnet-instrumentation-macos.zip . * ; cd ..
       - run: cd bin-nuget-packages ; zip -qq -r ../opentelemetry-dotnet-instrumentation-nuget-packages.zip . * ; cd ..
       - run: cp installation-scripts-windows-2022/otel-dotnet-auto-install.sh ./otel-dotnet-auto-install.sh
       - run: cp installation-scripts-windows-2022/OpenTelemetry.DotNet.Auto.psm1 ./OpenTelemetry.DotNet.Auto.psm1
diff --git a/.github/workflows/verify-test.yml b/.github/workflows/verify-test.yml
index 00ffbf6e20..d796cf478f 100644
--- a/.github/workflows/verify-test.yml
+++ b/.github/workflows/verify-test.yml
@@ -22,7 +22,7 @@ jobs:
             containers: windows
           - machine: ubuntu-20.04
             containers: linux
-          - machine: macos-12
+          - machine: macos-13
             containers: none
           - machine: otel-linux-arm64
             containers: linux
diff --git a/CHANGELOG.md b/CHANGELOG.md
index ff20da4b27..804948ae55 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -20,6 +20,9 @@ This component adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.h
 
 ### Removed
 
+- Support for macOS Monterey 12 x64.
+  macOs libraries are built and tested against [macOS Ventura 13 x64](https://github.com/actions/runner-images/blob/main/images/macos/macos-13-Readme.md).
+
 ### Fixed
 
 ## [1.9.0](https://github.com/open-telemetry/opentelemetry-dotnet-instrumentation/releases/tag/v1.9.0)
diff --git a/build/Build.NuGet.Steps.cs b/build/Build.NuGet.Steps.cs
index dc56c1b6a5..a456b0d239 100644
--- a/build/Build.NuGet.Steps.cs
+++ b/build/Build.NuGet.Steps.cs
@@ -53,7 +53,7 @@ partial class Build
                 "bin-alpine-arm64/linux-musl-arm64",
                 "bin-ubuntu-20.04/linux-x64",
                 "bin-otel-linux-arm64/linux-arm64",
-                "bin-macos-12/osx-x64",
+                "bin-macos-13/osx-x64",
                 "bin-windows-2022/win-x64",
                 "bin-windows-2022/win-x86"
             };
diff --git a/docs/README.md b/docs/README.md
index 6633f5319b..e1d30d3bb5 100644
--- a/docs/README.md
+++ b/docs/README.md
@@ -107,7 +107,7 @@ CI tests run against the following operating systems:
 - [CentOS 7 x64](https://github.com/open-telemetry/opentelemetry-dotnet-instrumentation/blob/main/docker/centos-build.dockerfile)
   (.NET 8 is not supported)
 - [CentOS Stream 9 x64](https://github.com/open-telemetry/opentelemetry-dotnet-instrumentation/blob/main/docker/centos-stream9.dockerfile)
-- [macOS Monterey 12 x64](https://github.com/actions/runner-images/blob/main/images/macos/macos-12-Readme.md)
+- [macOS Ventura 13 x64](https://github.com/actions/runner-images/blob/main/images/macos/macos-13-Readme.md)
 - [Microsoft Windows Server 2022 x64](https://github.com/actions/runner-images/blob/main/images/windows/Windows2022-Readme.md)
 - [Ubuntu 20.04 LTS x64](https://github.com/actions/runner-images/blob/main/images/ubuntu/Ubuntu2004-Readme.md)
 - Ubuntu 22.04 LTS ARM64
diff --git a/docs/developing.md b/docs/developing.md
index 90cda370c0..727b06e10b 100644
--- a/docs/developing.md
+++ b/docs/developing.md
@@ -89,7 +89,7 @@ it assumes that the code is run from the root of the repository and the CI
 artifacts we added to `~/Downloads/`:
 
 ```PowerShell
-$artifacts = @("bin-alpine", "bin-centos", "bin-macos-12", "bin-windows-2022")
+$artifacts = @("bin-alpine", "bin-centos", "bin-macos-13", "bin-windows-2022")
 $destFolder = "./bin/ci-artifacts/"
 $zipFilesFolder = "~/Downloads/"