diff --git a/qualang_tools/wirer/README.md b/qualang_tools/wirer/README.md
index 6859d7e5..9dac0ee9 100644
--- a/qualang_tools/wirer/README.md
+++ b/qualang_tools/wirer/README.md
@@ -113,6 +113,18 @@ instruments.add_octave(indices=1)
 instruments.add_lf_fem(controller=1, slots=[1])
 instruments.add_mw_fem(controller=1, slots=[2])
 ```
+#### Setups with External Mixers
+Note: An **external mixer** is defined as abstractly as a combined, IQ-upconverter and IQ-downconverter instrument.
+```python
+# Single LF-FEM and 2x External Mixers
+instruments.add_lf_fem(controller=1, slots=[1])
+instruments.add_external_mixer(indices=[1, 2])
+```
+```python
+# Single OPX+ and 2x External Mixers
+instruments.add_opx_plus(controllers=[1, 2])
+instruments.add_external_mixer(indices=[1, 2])
+```
 <details>
 <summary>Image</summary>
 <img alt="Empty OPX1000" src=".img/empty_opx1000.png">
diff --git a/qualang_tools/wirer/instruments/instruments.py b/qualang_tools/wirer/instruments/instruments.py
index 1689b1fb..0fd2e991 100644
--- a/qualang_tools/wirer/instruments/instruments.py
+++ b/qualang_tools/wirer/instruments/instruments.py
@@ -25,6 +25,9 @@ def __init__(self):
 
     def add_external_mixer(self, indices: Union[List[int], int]):
         """
+        Add an external mixer, which is defined abstractly as a combined, IQ-upconverter and
+        IQ-downconverter.
+
         `indices` (List[int] | int): Can be one or more indices for one or more external mixers.
         """
         if isinstance(indices, int):
diff --git a/qualang_tools/wirer/wirer/channel_specs.py b/qualang_tools/wirer/wirer/channel_specs.py
index f759ee15..1259bf91 100644
--- a/qualang_tools/wirer/wirer/channel_specs.py
+++ b/qualang_tools/wirer/wirer/channel_specs.py
@@ -15,7 +15,7 @@
     InstrumentChannelMwFemDigitalOutput,
     InstrumentChannelLfFemDigitalOutput,
     InstrumentChannelOctaveDigitalInput,
-    InstrumentChannelExternalMixerDigitalInput,
+    InstrumentChannelExternalMixerDigitalInput
 )
 
 # A channel template is a partially filled InstrumentChannel object
@@ -112,6 +112,29 @@ def __init__(self, index: int = None, rf_in: int = None, rf_out: int = None):
 
 
 class ChannelSpecLfFemBasebandAndOctave(ChannelSpec):
+    def __init__(
+            self,
+            con: int = None,
+            slot: int = None,
+            in_port_i: int = None,
+            in_port_q: int = None,
+            out_port_i: int = None,
+            out_port_q: int = None,
+            octave_index: int = None,
+            rf_in: int = None,
+            rf_out: int = None,
+    ):
+        super().__init__()
+        self.channel_templates = [
+            InstrumentChannelLfFemInput(con=con, slot=slot, port=in_port_i),
+            InstrumentChannelLfFemInput(con=con, slot=slot, port=in_port_q),
+            InstrumentChannelLfFemOutput(con=con, slot=slot, port=out_port_i),
+            InstrumentChannelLfFemOutput(con=con, slot=slot, port=out_port_q),
+            InstrumentChannelOctaveInput(con=octave_index, port=rf_in),
+            InstrumentChannelOctaveOutput(con=octave_index, port=rf_out),
+        ]
+
+class ChannelSpecLfFemBasebandAndExternalMixer(ChannelSpec):
     def __init__(
         self,
         con: int = None,
@@ -120,9 +143,7 @@ def __init__(
         in_port_q: int = None,
         out_port_i: int = None,
         out_port_q: int = None,
-        octave_index: int = None,
-        rf_in: int = None,
-        rf_out: int = None,
+        mixer_index: int = None,
     ):
         super().__init__()
         self.channel_templates = [
@@ -130,12 +151,34 @@ def __init__(
             InstrumentChannelLfFemInput(con=con, slot=slot, port=in_port_q),
             InstrumentChannelLfFemOutput(con=con, slot=slot, port=out_port_i),
             InstrumentChannelLfFemOutput(con=con, slot=slot, port=out_port_q),
-            InstrumentChannelOctaveInput(con=octave_index, port=rf_in),
-            InstrumentChannelOctaveOutput(con=octave_index, port=rf_out),
+            InstrumentChannelExternalMixerInput(con=mixer_index, port=1),
+            InstrumentChannelExternalMixerOutput(con=mixer_index, port=1),
         ]
 
 
 class ChannelSpecOpxPlusBasebandAndOctave(ChannelSpec):
+    def __init__(
+            self,
+            con: int = None,
+            in_port_i: int = None,
+            in_port_q: int = None,
+            out_port_i: int = None,
+            out_port_q: int = None,
+            octave_index: int = None,
+            rf_in: int = None,
+            rf_out: int = None,
+    ):
+        super().__init__()
+        self.channel_templates = [
+            InstrumentChannelOpxPlusInput(con=con, port=in_port_i),
+            InstrumentChannelOpxPlusInput(con=con, port=in_port_q),
+            InstrumentChannelOpxPlusOutput(con=con, port=out_port_i),
+            InstrumentChannelOpxPlusOutput(con=con, port=out_port_q),
+            InstrumentChannelOctaveInput(con=octave_index, port=rf_in),
+            InstrumentChannelOctaveOutput(con=octave_index, port=rf_out),
+        ]
+
+class ChannelSpecOpxPlusBasebandAndExternalMixer(ChannelSpec):
     def __init__(
         self,
         con: int = None,
@@ -143,9 +186,7 @@ def __init__(
         in_port_q: int = None,
         out_port_i: int = None,
         out_port_q: int = None,
-        octave_index: int = None,
-        rf_in: int = None,
-        rf_out: int = None,
+        mixer_index: int = None,
     ):
         super().__init__()
         self.channel_templates = [
@@ -153,8 +194,8 @@ def __init__(
             InstrumentChannelOpxPlusInput(con=con, port=in_port_q),
             InstrumentChannelOpxPlusOutput(con=con, port=out_port_i),
             InstrumentChannelOpxPlusOutput(con=con, port=out_port_q),
-            InstrumentChannelOctaveInput(con=octave_index, port=rf_in),
-            InstrumentChannelOctaveOutput(con=octave_index, port=rf_out),
+            InstrumentChannelExternalMixerInput(con=mixer_index, port=1),
+            InstrumentChannelExternalMixerOutput(con=mixer_index, port=1),
         ]
 
 
@@ -192,8 +233,11 @@ def __init__(self, con: int = None, in_port: int = None):
 lf_fem_spec = ChannelSpecLfFemSingle
 lf_fem_iq_spec = ChannelSpecLfFemBaseband
 lf_fem_iq_octave_spec = ChannelSpecLfFemBasebandAndOctave
+lf_fem_iq_ext_mixer_spec = ChannelSpecLfFemBasebandAndExternalMixer
 opx_spec = ChannelSpecOpxPlusSingle
 opx_iq_spec = ChannelSpecOpxPlusBaseband
 opx_iq_octave_spec = ChannelSpecOpxPlusBasebandAndOctave
+opx_iq_ext_mixer_spec = ChannelSpecOpxPlusBasebandAndExternalMixer
 octave_spec = ChannelSpecOctave
+ext_mixer_spec = ChannelSpecExternalMixer
 opx_dig_spec = ChannelSpecOpxPlusDigital