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feat(route): pubscholar #15788
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<title>「Open Access」Polymorphic phase transition in CoCrNi medium-entropy alloy under impact loadings</title>
<description>Polymorphic phase transition in metallic materials under high pressure is a critical aspect of dynamic properties and has been attracting a great interest. Despite the extensive researches have been made on understanding of this phase transition in traditional single-principal element alloys, little is known about the phase transition in recently emergent multi-principal medium and high entropy alloys, especially compressed under high strain rates. In this work, based on molecular dynamic simulations, three impact loading strategies with distinct loading paths, such as single-shock, double-shock and ramp-wave loading are carried out on the single crystalline CoCrNi medium-entropy alloy (MEA) to investigate the phase transition under high strain-rate compression. Careful characterizations show that the phase transition of CoCrNi MEA is loading-path dependent, as evidenced by the significant differences in macroscopic pressure evolution and microscopic structural phase transition among the samples under various thermodynamic paths. An intriguing pressure "overshoot" is found and demonstrated as the characteristic of the critical structural phase transition from face-centered cubic (FCC) structure to hexagonal-close-packed (HCP) structure mediated by body-centered cubic (BCC) like clusters. We show that such loading-path dependence is attributed to the strain rate and temperature rise in the loading process, which control the evolution of microstructure and deformation field. The inherent correlation between the atomistic process of phase transition and loading strategies results in polymorphic phase transition under high strain rates. These findings shed new light on the nature of impact phase transition of multi-principal alloys.<br><a href="https://doaj.org/article/baa3af735a9e46ccb757368248b2d004">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/c0852ed2508fb4b26a2c88f07d12205b21e3bc4f4619f503d1b374a5085e7c12578dab267526d267d6b673147d6a2a6d</link>
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<pubDate>Invalid Date</pubDate>
<author>Wenbo Zhou; Fuhua Cao; Zengyu Yang; Tong Li; Yangyang Niu; 陈艳; Haiying Wang; 戴兰宏</author>
<category>Medium-entropy alloy</category>
<category>Phase transition</category>
<category>Shock compression</category>
<category>Ramp-wave</category>
<category>Loading path</category>
</item>
<item>
<title>「Open Access」Developmental impacts and toxicological hallmarks of silver nanoparticles across diverse biological models</title>
<description>Silver nanoparticles (AgNPs), revered for their antimicrobial prowess, have become ubiquitous in a range of products, from biomedical equipment to food packaging. However, amidst their rising popularity, concerns loom over their possible detrimental effects on fetal development and subsequent adult life. This review delves into the developmental toxicity of AgNPs across diverse models, from aquatic species like zebrafish and catfish to mammalian rodents and in vitro embryonic stem cells. Our focus encom-passes the fate of AgNPs in different contexts, elucidating associated hazardous results such as embry-otoxicity and adverse pregnancy outcomes. Furthermore, we scrutinize the enduring adverse impacts on offspring, spanning impaired neurobehavior function, reproductive disorders, cardiopulmonary lesions, and hepatotoxicity. Key hallmarks of developmental harm are identified, encompassing redox imbal-ances, inflammatory cascades, DNA damage, and mitochondrial stress. Notably, we explore potential explanations, linking immunoregulatory dysfunction and disrupted epigenetic modifications to AgNPs-induced developmental failures. Despite substantial progress, our understanding of the developmental risks posed by AgNPs remains incomplete, underscoring the urgency of further research in this critical area.(c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/cd6e18d0ee614567bcac27995c799ca9">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/6d8fe270d1d7fe40b977965820705803b3f0703a2ac8a26e45eb604752a3956b583d17b7e77ce1e2e9c3305de6ffe855</link>
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<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Wang, Yan; Han, Yapeng; Xu, DeXiang</author>
<category>Silver nanoparticles (AgNPs)</category>
<category>Developmental toxicity</category>
<category>Maternal exposure</category>
<category>Fetal development</category>
<category>Redox imbalance</category>
<category>Mitochondrial dysfunction</category>
</item>
<item>
<title>「Open Access」Concentration-dependent effects of reductive pulmonary inhalants on ultrafine particle-induced oxidative stress: Insights for health ri...</title>
<description>The impact of reductive pulmonary inhalants on ultrafine particles (UFPs)-induced pulmonary oxidative stress remains a crucial consideration, yet the concentration-dependent effects of these inhalants have remained unexplored. Here we synthesized composite UFPs simulating atmospheric UFPs, primarily composed of metals and quinones. We subjected these UFPs to varying concentrations (0-7000 mu M) of two reductive pulmonary inhalants, N-acetylcysteine and salbutamol, to assess their influence on oxidative potential, measured through the dithiothreitol assay (OPDTT). Simultaneously, we analysed the soluble metal content of UFPs to uncover potential relationships between oxidative potential and metal solubility. Our results unveil a dual role played by these inhalants in shaping the OPDTT of composite UFPs. Specifically, OPDTT generally increased as inhalant concentrations rose from 0 to 300 mu M. However, an intriguing reversal occurred when concentrations exceeded 500 mu M, resulting in a decline in OPDTT. Relative to untreated UFPs, these inhalants induced promotion and inhibition effects within concentration ranges of 100-500 and &gt;1000 mu M, respectively. While no significant correlation emerged between OPDTT and soluble metal content as inhalant concentrations ranged from 0 to 7000 mu M, noteworthy positive correlations emerged at lower inhalant concentrations (e.g., N-acetylcysteine at 0-300 mu M). These findings provide insights into the potential influence of reductive pulmonary inhalants on health risks associated with UFP exposure, further underscoring the need for continued research in this critical area.<br><a href="https://doaj.org/article/a0cc678d8d9f42899f53cd680d38fb6d">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/a5fb0ed75bcbb6e49c8cdf332e45e614e4682ed657675abf0bac538f1343de4822552779d4e72ea6a08d1cdb527d6687</link>
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<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Yu, Yaqi; Zhu, Tong</author>
<category>Concentration-dependent effects</category>
<category>Oxidative potential</category>
<category>Reductive pulmonary inhalants</category>
<category>Soluble metals</category>
<category>Simulated atmospheric ultrafine particles</category>
</item>
<item>
<title>「Open Access」Knowledge-guided machine learning reveals pivotal drivers for gas-to-particle conversion of atmospheric nitrate</title>
<description>Particulate nitrate, a key component of fine particles, forms through the intricate gas-to-particle con-version process. This process is regulated by the gas-to-particle conversion coefficient of nitrate (epsilon(NO3 =)). The mechanism between epsilon(NO3 =) and its drivers is highly complex and nonlinear, and can be charac-terized by machine learning methods. However, conventional machine learning often yields results that lack clear physical meaning and may even contradict established physical/chemical mechanisms due to the influence of ambient factors. It urgently needs an alternative approach that possesses transparent physical interpretations and provides deeper insights into the impact of epsilon(NO3 =). Here we introduce a supervised machine learning approachdthe multilevel nested random forest guided by theory ap-proaches. Our approach robustly identifies NH4 thorn , SO42 =, and temperature as pivotal drivers for epsilon(NO3 =). Notably, substantial disparities exist between the outcomes of traditional random forest analysis and the anticipated actual results. Furthermore, our approach underscores the significance of NH4 thorn during both daytime (30%) and nighttime (40%) periods, while appropriately downplaying the influence of some less relevant drivers in comparison to conventional random forest analysis. This research underscores the transformative potential of integrating domain knowledge with machine learning in atmospheric studies. (c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/91342b2dce554f2090bf217fa578188e">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/9277c21d65bfd7afd92f8885b36c61afdf2186bdfff16d2d1468fc02567b48523cccc6c4d09d5b7d9740bccdb72cd191</link>
<guid isPermaLink="false">https://pubscholar.cn/articles/9277c21d65bfd7afd92f8885b36c61afdf2186bdfff16d2d1468fc02567b48523cccc6c4d09d5b7d9740bccdb72cd191</guid>
<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Xu, Bo; Yu, Haofei; Shi, Zongbo; Liu, Jinxing; Wei, Yuting; Zhang, Zhongcheng; Huangfu, Yanqi; Xu, Han; Li, Yue; Zhang, Linlin; Feng, Yinchang; Shi, Guoliang</author>
<category>Machine learning</category>
<category>Data driven</category>
<category>Theoretical approach</category>
<category>Domain knowledge</category>
<category>Guide</category>
</item>
<item>
<title>「Open Access」H2 mediated mixed culture microbial electrosynthesis for high titer acetate production from CO2</title>
<description>Microbial electrosynthesis (MES) converts CO2 into value-added products such as volatile fatty acids (VFAs) with minimal energy use, but low production titer has limited scale-up and commercialization. Mediated electron transfer via H2 on the MES cathode has shown a higher conversion rate than the direct biofilm-based approach, as it is tunable via cathode potential control and accelerates electrosynthesis from CO2. Here we report high acetate titers can be achieved via improved in situ H2 supply by nickel foam decorated carbon felt cathode in mixed community MES systems. Acetate concentration of 12.5 g L-1 was observed in 14 days with nickel-carbon cathode at a poised potential of-0.89 V (vs. standard hydrogen electrode, SHE), which was much higher than cathodes using stainless steel (5.2 g L-1) or carbon felt alone (1.7 g L-1) with the same projected surface area. A higher acetate con-centration of 16.0 g L-1 in the cathode was achieved over long-term operation for 32 days, but crossover was observed in batch operation, as additional acetate (5.8 g L-1) was also found in the abiotic anode chamber. We observed the low Faradaic efficiencies in acetate production, attributed to partial H2 utilization for electrosynthesis. The selective acetate production with high titer demonstrated in this study shows the H2-mediated electron transfer with common cathode materials carries good promise in MES development.(c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/06635a88302448bba000ad33efe0adde">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/e4d6d7a0de66c9a5ddefa727c0e953498f1407c5073e85ed444aeab32c9e51696b881b5a70601e975b0195eee1231603</link>
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<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Bian, Yanhong; Leininger, Aaron; May, Harold D; Ren, Zhiyong Jason</author>
<category>Microbial electrosynthesis</category>
<category>Indirect electron transfer</category>
<category>CO 2 electrolysis</category>
<category>VFAs production</category>
</item>
<item>
<title>「Open Access」The 2022 report of synergetic roadmap on carbon neutrality and clean air for China: Accelerating transition in key sectors</title>
<description>China is now confronting the intertwined challenges of air pollution and climate change. Given the high synergies between air pollution abatement and climate change mitigation, the Chinese government is actively promoting synergetic control of these two issues. The Synergetic Roadmap project was launched in 2021 to track and analyze the progress of synergetic control in China by developing and monitoring key indicators. The Synergetic Roadmap 2022 report is the first annual update, featuring 20 indicators across five aspects: synergetic governance system and practices, progress in structural transition, air pollution and associated weather-climate interactions, sources, sinks, and mitigation pathway of atmospheric composition, and health impacts and benefits of coordinated control. Compared to the comprehensive review presented in the 2021 report, the Synergetic Roadmap 2022 report places particular emphasis on progress in 2021 with highlights on actions in key sectors and the relevant milestones. These milestones include the proportion of non-fossil power generation capacity surpassing coal-fired capacity for the first time, a decline in the production of crude steel and cement after years of growth, and the surging penetration of electric vehicles. Additionally, in 2022, China issued the first national policy that synergizes abatements of pollution and carbon emissions, marking a new era for China's pollution-carbon co-control. These changes highlight China's efforts to reshape its energy, economic, and transportation structures to meet the demand for synergetic control and sustainable development. Consequently, the country has witnessed a slowdown in carbon emission growth, improved air quality, and increased health benefits in recent years.(c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/6d3582cee0a7422eba8b42b95490dd3b">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/7e319c4d6f891f32e35c715d4620ba1ca5cf20f6178c57f9322c660917115b09b3905ffc4cdbe77ffd9b62640dd4a5d8</link>
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<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Lei, Yu; Yin, Zhicong; Lu, Xi; Zhang, Qiang; Gong, Jicheng; Cai, Bofeng; Cai, Cilan; Chai, Qimin; Chen, Huopo; Chen, Renjie; Chen, Shi; Chen, Wenhui; Cheng, Jing; Chi, Xiyuan; Dai, Hancheng; Feng, Xiangzhao; Geng, Guannan; Hu, Jianlin; Hu, Shan; Huang, Cunrui; Li, Tiantian; Li, Wei; Li, Xiaomei; Liu, Jun; Liu, Xin; Liu, Zhu; Ma, Jinghui; Qin, Yue; Tong, Dan; Wang, Xuhui; Wang, Xuying; Wu, Rui; Xiao, Qingyang; Xie, Yang; Xu, Xiaolong; Xue, Tao; Yu, Haipeng; Zhang, Da; Zhang, Ning; Zhang, Shaohui; Zhang, Shaojun; Zhang, Xian; Zhang, Xin; Zhang, Zengkai; Zheng, Bo; Zheng, Yixuan; Zhou, Jian; Zhu, Tong; Wang, Jinnan; He, Kebin</author>
<category>Synergetic roadmap</category>
<category>Carbon neutrality</category>
<category>Clean air</category>
</item>
<item>
<title>「Open Access」Salinity causes differences in stratigraphic methane sources and sinks</title>
<description>Methane metabolism, driven by methanogenic and methanotrophic microorganisms, plays a pivotal role in the carbon cycle. As seawater intrusion and soil salinization rise due to global environmental shifts, understanding how salinity affects methane emissions, especially in deep strata, becomes imperative. Yet, insights into stratigraphic methane release under varying salinity conditions remain sparse. Here we investigate the effects of salinity on methane metabolism across terrestrial and coastal strata (15-40 m depth) through in situ and microcosm simulation studies. Coastal strata, exhibiting a salinity level five times greater than terrestrial strata, manifested a 12.05% decrease in total methane production, but a staggering 687.34% surge in methane oxidation, culminating in 146.31% diminished methane emissions. Salinity emerged as a significant factor shaping the methane-metabolizing microbial community's dynamics, impacting the methanogenic archaeal, methanotrophic archaeal, and methanotrophic bacterial communities by 16.53%, 27.25%, and 22.94%, respectively. Furthermore, microbial interactions influenced strata system methane metabolism. Metabolic pathway analyses suggested Atribacteria JS1's potential role in organic matter decomposition, facilitating methane production via Methanofastidiosales. This study thus offers a comprehensive lens to comprehend stratigraphic methane emission dynamics and the overarching factors modulating them.(c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/682c880c16364c0997fc9bc8489c9484">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/2fa95248574f9049d7107f7b0e409979d1170d5fe02fb74338a89c3b54b443894d3463412929afb8ea0685bccebf5688</link>
<guid isPermaLink="false">https://pubscholar.cn/articles/2fa95248574f9049d7107f7b0e409979d1170d5fe02fb74338a89c3b54b443894d3463412929afb8ea0685bccebf5688</guid>
<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Qu, Ying; Zhao, Yuxiang; Yao, Xiangwu; Wang, Jiaqi; Liu, Zishu; Hong, Yi; Zheng, Ping; Wang, Lizhong; Hu, Baolan</author>
<category>Shallow gas strata</category>
<category>Salinity</category>
<category>Methane emission</category>
<category>Microbial community</category>
<category>Microbial interactions</category>
</item>
<item>
<title>「Open Access」Data-driven interpretable analysis for polysaccharide yield prediction</title>
<description>Cornstalks show promise as a raw material for polysaccharide production through xylanase. Rapid and accurate prediction of polysaccharide yield can facilitate process optimization, eliminating the need for extensive experimentation in actual production to refine reaction conditions, thereby saving time and costs. However, the intricate interplay of enzymatic factors poses challenges in predicting and optimizing polysaccharide yield accurately. Here, we introduce an innovative data-driven approach leveraging multiple artificial intelligence techniques to enhance polysaccharide production. We propose a machine learning framework to identify highly accurate polysaccharide yield prediction modeling methods and uncover optimal enzymatic parameter combinations. Notably, Random Forest (RF) and eXtreme Gradient Boost (XGB) demonstrate robust performance, achieving prediction accuracies of 93.0% and 95.6%, respectively, while an independently developed deep neural network (DNN) model achieves 91.1% accuracy. A feature importance analysis of XGB reveals the enzyme solution volume's dominant role (43.7%), followed by time (20.7%), substrate concentration (15%), temperature (15%), and pH (5.6%). Further interpretability analysis unveils complex parameter interactions and potential optimization strategies. This data-driven approach, incorporating machine learning, deep learning, and interpretable analysis, offers a viable pathway for polysaccharide yield prediction and the potential recovery of various agricultural residues. (c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).<br><a href="https://doaj.org/article/a58b5160ab574288b2550d79c11081ae">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/e9114a53832c165523068fce921874ccc1a599eaaac2602e4177ec26a5fb51e20f0cf9223f459366893c20019429e6cd</link>
<guid isPermaLink="false">https://pubscholar.cn/articles/e9114a53832c165523068fce921874ccc1a599eaaac2602e4177ec26a5fb51e20f0cf9223f459366893c20019429e6cd</guid>
<pubDate>Tue, 30 Apr 2024 16:00:00 GMT</pubDate>
<author>Tian, Yushi; Yang, Xu; Chen, Nianhua; Li, Chunyan; Yang, Wulin</author>
<category>Cornstalk</category>
<category>Xylanase</category>
<category>Polysaccharide yield prediction</category>
<category>Machine learning</category>
<category>Model interpretability</category>
</item>
<item>
<title>「Open Access」The landscape of inpatient admissions for alcoholic hepatitis in the era of early liver transplantation</title>
<description>Introduction and Objectives: Liver transplant (LT) is a recent option available in the United States (US) to treat those with severe, refractory alcoholic hepatitis (AH). We examined changes in clinical characteristics of patients admitted with AH and tracked hospital outcomes as practice changes involving LT have shifted.Materials and Methods: Using the National Inpatient Sample, we performed a cross-sectional analysis of patients admitted with AH during the years 2016-2020 in the US. Differences in clinical characteristics over time were assessed. To compare outcomes between 2016-2017 (when LT was less common) and 2018 -2020 (when LT was more common), we conducted linear and logistic regression. Propensity-score matching was used compare outcomes between patients with and without LT.Results: From 2016-2017 to 2018-2020, patients admitted with AH tended to have a higher frequency of infection (p = 0.006), hepatorenal syndrome (&lt;0.001), and ascites (&lt;0.001). Hospital costs and length of stay (LOS) were highest in transplant hospitals, and costs rose over time in both non-transplant (NT) teaching and non-teaching hospitals (p &lt; 0.001). Mortality decreased in NT teaching hospitals aOR 0.7 (95% CI: 0.6-0.8) and slightly decreased in NT non-teaching hospitals aOR 0.7 (95% CI: 0.5-1.0). In the propensity-matched cohort involving LT versus non-LT patients, there was a 10% absolute reduction in-hospital mortality, but this came at a higher cost (p &lt; 0.001) and length of stay (p &lt; 0.001).Conclusions: The severity of AH has been increasing over time, yet mortality has declined, after adjusting for severity of disease. Patients who underwent LT survived; however, the healthcare burden of LT is substantial.(c) 2023 Fundacion Clinica Medica Sur, A.C. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)<br><a href="https://doaj.org/article/6cde91f2c3364b969de8ce27706aba21">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/4ffceb2479c67052a07ef09dc39d4126bdb0ef88f9f95685c8e25dffd5abe41e2c878ca7c3e8508f14ea4b5dc17ac31e</link>
<guid isPermaLink="false">https://pubscholar.cn/articles/4ffceb2479c67052a07ef09dc39d4126bdb0ef88f9f95685c8e25dffd5abe41e2c878ca7c3e8508f14ea4b5dc17ac31e</guid>
<pubDate>Thu, 29 Feb 2024 16:00:00 GMT</pubDate>
<author>Prakash, Shahana; Tanaka, Tomohiro</author>
<category>Alcoholic hepatitis</category>
<category>Liver transplant</category>
<category>Cost</category>
<category>Hepatology</category>
</item>
<item>
<title>「Open Access」Reactive oxygen species (ROS)-mediated M1 macrophage-dependent nanomedicine remodels inflammatory microenvironment for osteoarthritis r...</title>
<description>Osteoarthritis (OA) is a common chronic inflammatory disorder. Effective remodeling of inflammatory microenvironment in the joint is a promising strategy to prevent OA. However, current drugs remain unsatisfactory due to a lack of targeted and effective ways for relieving inflammatory conditions in OA joints. Bortezomib (BTZ), a proteasome inhibitor, could effectively inhibit proinflammatory cytokines but with poor accumulation in the inflammatory tissues. To overcome the shortcomings of BTZ delivery and to improve the efficacy of OA therapy, herein, we designed a novel nanomedicine (denoted as BTZ@PTK) by the co-assembly of BTZ and an amphiphilic copolymer (denoted as PTK) with ROS-cleaved thioketal (TK) linkages. The TK units in BTZ@PTK are first cleaved by the excessive ROS at OA sites, and then triggered the controlled release of BTZ, resulting in the accurate delivery and the inflammatory microenvironment remodeling. Accordingly, BTZ@PTK suppressed ROS generation and proinflammatory cytokines while promoting M1 macrophage apoptosis in lipopolysaccharide (LPS)-activated RAW264.7 macrophages or LPS/IFN-gamma-treated primary macrophages, which leads to a better effect than BTZ. In OA mice, BTZ@PTK passively accumulates into inflamed joints to attenuate pain sensitivity and gait abnormality. Importantly, BTZ@PTK treatment successfully ameliorates synovitis with the reduction of synovial hyperplasia and synovitis scores by suppressing M1 macrophage polarization and promoting M1 macrophage apoptosis in the synovium, thereby delaying cartilage damage. Collectively, BTZ@PTK can effectively modulate inflammatory microenvironment for OA recession by activating M1 macrophage apoptosis and inhibiting M1macrophage-mediated inflammatory response.<br><a href="https://doaj.org/article/034e04ad67e14c08a78ae108221e0073">「Open Access」DOAJ</a></description>
<link>https://pubscholar.cn/articles/6564c2661bbdf1cbb65c84e9f21b0a989ad8001789f89d36065dd70c01a05276bc263d58c1cb6c5ae411b720dec0c4a8</link>
<guid isPermaLink="false">https://pubscholar.cn/articles/6564c2661bbdf1cbb65c84e9f21b0a989ad8001789f89d36065dd70c01a05276bc263d58c1cb6c5ae411b720dec0c4a8</guid>
<pubDate>Thu, 29 Feb 2024 16:00:00 GMT</pubDate>
<author>Xue, Chunchun; Tian, Jia; Cui, Zepeng; Liu, Yang; Sun, Dawei; Xiong, Mengting; Yi, Nanxing; Wang, Kaiqiang; Li, Xiaofeng; Xu, Hao; Wang, Yongjun; Zhang, Weian; Liang, Qianqian</author>
<category>Reactive oxygen species</category>
<category>Osteoarthritis</category>
<category>Inflammatory microenvironment</category>
<category>Macrophages polarization</category>
<category>Apoptosis</category>
</item>
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</rss> |
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Involved Issue / 该 PR 相关 Issue
Close #14363
Example for the Proposed Route(s) / 路由地址示例
New RSS Route Checklist / 新 RSS 路由检查表
Puppeteer
Note / 说明