Maybe like this

conanfile.py

@@ -85,6 +85,13 @@ def config_options(self):
         if self.settings.os == "Windows":
             del self.options.fPIC
 
+    def generate_vcpkg(self):
+        # Install vcpkg dependencies
+        self.vcpkg_dir = os.environ["VCPKG_ROOT"]
+        print("vcpkg_dir: ", vcpkg_dir)
+        self.vcpkg_exe = f"{self.vcpkg_dir}/vcpkg.exe" if self.settings.os == "Windows" else f"{self.vcpkg_dir}/vcpkg"
+        self.run(f"{self.vcpkg_exe} install --manifest")
+
     def generate(self):
         generator = None
         if self.settings.os == "Macos":
@@ -115,19 +122,13 @@ def generate(self):
         # Set some build options
         tc.variables["MV_UNITY_BUILD"] = "ON"
 
-        tc.generate()
+        # vcpkg settings
+        tc.variables["CMAKE_PROJECT_INCLUDE "] = os.path.join(self.vcpkg_dir, "scripts", "buildsystems", "vcpkg.cmake")
 
-        # Install vcpkg dependencies
-        vcpkg_dir = os.environ["VCPKG_ROOT"]
-        print("vcpkg_dir: ", vcpkg_dir)
-        #vcpkg_exe = f"{vcpkg_dir}/vcpkg.exe" if self.settings.os == "Windows" else f"{vcpkg_dir}/vcpkg"
-        #self.run(f"{vcpkg_exe} install --manifest")
+        tc.generate()
 
     def _configure_cmake(self):
         cmake = CMake(self)
-        # Set Conan's toolchain with CMAKE_PROJECT_INCLUDE to include Conan toolchain early
-        cmake.definitions["CMAKE_PROJECT_INCLUDE"] = os.path.join(self.build_folder, "conan_toolchain.cmake")
-        cmake.definitions["CMAKE_TOOLCHAIN_FILE"] = os.path.join(os.environ["VCPKG_ROOT"], "vcpkg/scripts/buildsystems/vcpkg.cmake")
         cmake.configure(build_script_folder="hdps/ExamplePlugins")
         cmake.verbose = True
         return cmake