prs_disparities

Figure 1 (GWAS participants over time)

• gwas_disparities_time.R

Figure 2 (GWAS catalog sites and pairwise ancestry LD matrices)

• gwas_sfs_pop.R and ld_matrices.py

Figure 3 (empirical R^2 across populations with EUR GWAS)

• multiethnic_prs_empirical.R

Figure 4 (compare symmetric prediction accuracy in BBJ and UKBB)

• Run same-sized holdout GWAS: run_holdout_gwas.py
• Compute PRS in holdout samples: run_prs_holdout.py
• Aggregate PRS statistics: holdout_ukbb_bbj_r2.R
• Plot R^2 values: plot_ukbb_bbj_r2.R