It is possible to predict the spectrum of e.g. a nucleobase in a nucleoside-nucleobase conversion.

Finding thermodynamic cycles in the metabolism

Create an open database for the thermodynamics of enzyme-catalyzed reactions (and other metabolism relevant thermodynamic data)

compare two-point UV/Vis spectroscopy read-out with spectral unmixing

When is it favorable to do two-step or one-pot coupled enzyme reactions?

When determining equilibrium constants of multi-substrate / multi-product reactions, their ratios affect the uncertainty of the result.

Thermodynamics can present itself as kinetic inhibition

Isolate the degradation product of fluoro-nucleosides

Try to observe with a microscope what is making an UV/Vis spectroscopy method fail

Determine the thermodynamic properties for nucleotide conversions